HRPP Supplemental Guidance Manual
Revision Date: April 3, 2023
The HRPP Supplemental Guidance Manual contains standalone Yale HRPP guidance documents, previously published on the Yale HRPP website, that address topics in human research protections in addition to material referenced in other HRPP manuals. The HRPP Supplemental Guidance Manual will be periodically updated to include timely and helpful guidance for the research community as the Yale HRPP becomes aware of new information and best practices relevant to the conduct of human subjects research.
Guidance: General Data Protection Regulation (GDPR) and Research
Revision Date: November 10, 2025
This guidance is to help researchers with a basic understanding of how the General Data Protection Regulation (GDPR) may affect their research.
Guidance: Research Repositories
Date: November 1, 2025
This guidance from the Yale HRPP outlines Yale University and Yale HRPP requirements for the creation and maintenance of research repositories.
Guidance: Use of Health Information Exchanges in Research
Revision Date: April 24, 2025
This guidance clarifies whether and how Epic’s Care Everywhere (CE) functionality may be used for purposes that may be considered research or both research and treatment.
Guidance: Sharing Data for Research Purposes
Revision Date: February 3, 2025
This guidance from the Yale HIPAA Privacy Office describes HIPAA-compliant methods and resources for sharing data with collaborators.
Guidance: Actions for IRB Approved Protocols After Loss of Funding or Sponsor Notice of Termination Revision
Date: April 30, 2025
This guidance from the Yale HRPP describes investigator responsibilities for when funding has been stopped or withdrawn.