Guidance: Depression and Suicidality in Human Subjects Research
Revision Date: August 17, 2026
Research studies that include measures for depression and suicidality should anticipate that certain participant responses may necessitate some level of intervention. A plan for how these research findings will be handled, should they arise, should be provided with the IRB protocol. Examples of acceptable plans are described in this document.
Guidance: General Data Protection Regulation (GDPR) and Research
Revision Date: November 10, 2025
This guidance is to help researchers with a basic understanding of how the General Data Protection Regulation (GDPR) may affect their research.
Guidance: Research Repositories
Date: November 1, 2025
This guidance from the Yale HRPP outlines Yale University and Yale HRPP requirements for the creation and maintenance of research repositories.
Guidance: Use of Health Information Exchanges in Research
Revision Date: April 24, 2025
This guidance clarifies whether and how Epic’s Care Everywhere (CE) functionality may be used for purposes that may be considered research or both research and treatment.
Guidance: Sharing Data for Research Purposes
Revision Date: February 3, 2025
This guidance from the Yale HIPAA Privacy Office describes HIPAA-compliant methods and resources for sharing data with collaborators.
Guidance: Actions for IRB Approved Protocols After Loss of Funding or Sponsor Notice of Termination Revision
Date: April 30, 2025
This guidance from the Yale HRPP describes investigator responsibilities for when funding has been stopped or withdrawn.
Reference Guide: Quality Improvement Projects
Revision Date: April 1, 2024
This document provides guidance regarding how to determine whether a proposed project meets the definition of Quality Improvement or Human Subjects Research.
Reference Guide: Blood Limit Guidelines for Adult and Pediatric Research
Rrevision Date: September 1, 2020
This document provides guidelines for assessing whether blood collection for research is appropriate for studies involving adults and/or pediatric populations.